The last use of the Akkadian language
The last use of the Akkadian language 1--343
?Have you asked yourselves when was the last use of the Akkadian language and the cuneiform script in Mesopotamia
After the fall of Babylon, Iraq passed through centuries of Achaemenid, Macedonian, Seleucid, and Parthian control.
As a result of this control, the ancient Mesopotamian peoples mixed with the new Parthian and Greek peoples, and each influenced the other.
During the Parthian rule, which extended from 126 BC until 226 AD, the use of the Akkadian language and the cuneiform script was limited to astronomical and mathematical texts, a few historical texts, and some economic documents. The last known cuneiform text dates back to the year 75 AD, and was an astronomical text.
During the Parthian era, we witnessed the end of the use of the Akkadian language and the cuneiform script in Mesopotamia forever, to be replaced by the widespread use of the Aramaic language and its alphabetic script.


Source: Lectures on ancient history/babylon the gate of gods/Amer Suleiman.